Informed by Sen’s capability approach [ 1 , 2 ], the Adult Social Care Outcomes Toolkit (ASCOT) is a family of instruments that measure social care-related quality of life (SCRQoL) [ 3 , 4 ]. SCRQoL refers to aspects of quality of life (QoL) that …

Patient-Reported Outcome Measures (PROMs) can be key tools for clinical decision-making. PROMs should be sufficiently reliable, valid, and responsive to reflect the patient’s perspective (e.g., feelings, daily functions, well-being etc.).

β-thalassemia is a rare hereditary hemoglobinopathy with a prevalence rate of 18 out of 100,000 [ 1 ]. Worldwide there are over 1 million people with β-thalassemia, with each year over 40,000 newborns diagnosed, nearly 62% (approximately 25,500) of …

Sickle cell disease (SCD) refers to a group of inherited disorders caused by mutations in the gene that encodes the β-subunit of adult hemoglobin ( HBB ). These mutations lead to the production of abnormal, sickled hemoglobin and chronic hemolytic …

The introduction of antiretroviral therapies (ARTs) and highly active ARTs has greatly reduced morbidity and mortality for people with HIV (PWH), with marked improvements in life expectancy seen since 1996 [ 1 ]. ARTs, however, are currently unable …

Patient reported outcome measures (PROMs) are evidence-based patient communication tools that have begun to gain popularity and implementation across several fields of medicine, especially in cancer care [ 1 ]. PROMs help better incorporate …

The quality of life (QOL) serves as a pivotal reference for assessing human health. However, there is a notable dearth of research focusing on the QOL of specific populations, particularly older adults. Prior studies have highlighted the …

With the intensification of global population aging, the health and quality of life of older people have become major global concerns [ 1 ]. Health-related quality of life (HRQoL) refers to the impact of an individual’s health status—encompassing …

This study is essential because it examines how Lebanon's economic crisis affects the lives of people with multiple sclerosis (MS). The main issue it addresses is how the crisis has limited patients' access to necessary treatments, impacting their …

This study addresses the need to understand how health-related quality of life (HQoL) impacts the overall survival (OS) of head and neck cancer (HNC) patients. By analyzing various HQoL indices and symptoms-specific outcomes, the study aims to …

Focal segmental glomerulosclerosis (FSGS) is a kidney disease characterized by scarring of the glomerulus, vessels which filter waste and excess fluids from the blood, and can ultimately lead to decline in kidney function and progression to kidney …

Patient-reported outcome measures (PROMs), defined as “a report coming directly from patients about how they feel or function without interpretation by healthcare professionals or anyone else” continue to figure prominently in quality-based …

Little is known about the effectiveness of health behaviour intervention in improving health-related quality of life (HRQOL) of people with Type 2 diabetes mellitus (T2DM) despite HRQOL being an important outcome in T2DM management. This study …

Sarcopenic obesity (SO) is complex phenotype that combines excess adiposity with a significant reduction in muscle mass and strength [ 1 , 2 ]. The clinical significance of SO is underscored by its association with more severe adverse health …

This study examines how minimal hepatic encephalopathy (MHE), a common condition in patients with cirrhosis, affects thinking and coordination. High ammonia levels in the blood are linked to cognitive issues and coordination problems, which may …

This study is needed to understand how different types of hip replacement surgeries affect the quality of life in patients who have broken the neck of their femur, which is a common injury in older adults. The key question this research addresses …

Breast cancer is a prevalent malignancy that affects women worldwide [ 1 ]. Adverse effects stemming from the disease and its treatments present a substantial risk to the physical, psychological, and social well-being of these individuals [ 2 , 3 …

Patient‑reported outcome measures (PROMs) play a key role in modern health care and research settings [ 1 ]. PROMs are questionnaires that can be used to assess patients’ health status and evaluate treatment impact from the patients’ perspectives.

Draft guidance from the U.S. Food and Drug Administration states that one can interpret a treatment effect on a clinical outcome assessment–based endpoint when expressed as some difference between group means. Recently, Trigg et al. examined …