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Quality of Life Research

15-04-2025

Quality of life and access to treatment for patients with multiple sclerosis during economic crisis: the Lebanese experience

Auteurs: Maya Zeineddine, Ghida Ismail, Malak Issa, Taghrid El-Hajj, Hassan Tfaily, Mohamad Dassouki, Elie Assaf, Halim Abboud, Pascale Salameh, Amal Al-Hajje, Farid Boumediene, Bassem Yamout

Gepubliceerd in: Quality of Life Research

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Abstract

Purpose

Multiple sclerosis (MS) is a demyelinating disease of the central nervous system that can lead to lifelong disability, significantly impacting patient’s quality of life (QOL). The current Lebanese economic crisis led to limited accessibility to MS therapies and had a major impact on QOL.The aim of this study was to assess QOL in a cohort of Lebanese MS patients, and its association with socio-demographic factors, disease characteristics, and treatment accessibility.

Methods

A cross-sectional, survey-based study was conducted between June and September 2022 in Lebanese patients with confirmed MS diagnosis as per the 2017 McDonald criteria. Structured questionnaires were used to obtain (1) socio-demographic and medical information, (2) QOL assessment using the MS International QOL questionnaire (MusiQoL), and (3) information related to barriers in accessing MS therapies. All questionnaires were administered via telephone call.

Results

A total of 350 MS patients were included in the study. Most participants (92.3%) were diagnosed with relapsing–remitting MS and were females (65.1%) with a mean age of 39.4 ± 11.4 years. The mean MusiQol global index was 69.2 ± 11.5. In the multivariate analysis, younger age, higher level of education, being employed, being married, living outside the capital Beirut, and having no physical disability were significantly associated with higher MusiQol global index scores. A total of 216 Lebanese MS patients (61.7%) had no access to MS treatments due to the economic crisis. Treatment discontinuation and lack of governmental or private insurance were significant predictors of lower MusiQol scores.

Conclusion

The economic crisis and resultant recession in Lebanon had a significantly negative impacted on QOL and treatment accessibility of MS patients. Socio-demographic factors, disease characteristics and treatment accessibility were strong predictors of QOL.
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Metagegevens
Titel
Quality of life and access to treatment for patients with multiple sclerosis during economic crisis: the Lebanese experience
Auteurs
Maya Zeineddine
Ghida Ismail
Malak Issa
Taghrid El-Hajj
Hassan Tfaily
Mohamad Dassouki
Elie Assaf
Halim Abboud
Pascale Salameh
Amal Al-Hajje
Farid Boumediene
Bassem Yamout
Publicatiedatum
15-04-2025
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-025-03970-7