Wellbeing and health-related quality of life (HRQoL) are important parts of positive child development and health [ 1 ]. Poor wellbeing among children and youth is an increasing concern worldwide [ 2 ], and in Denmark, a decrease in wellbeing has …

The hepatitis C virus (HCV) has a dramatic global impact, with an estimated 50 million people with chronical infection by 2022 and about 1.5 million new infections occurring annually [ 1 ]. While some people with HCV may be asymptomatic, others may …

Health Technology Assessment (HTA) is a crucial component of healthcare systems, essential for prioritizing interventions and allocating resources effectively [ 1 ]. It involves the systematic evaluation of health technologies, providing …

Healthcare systems are facing the challenge of an ageing population, increased rates of chronic disease and rising healthcare costs [ 1 – 3 ]. This challenge is likely to escalate, with the global number of people aged 60 years and over projected …

Few health-related constructs or measures have received a critical evaluation in terms of measurement equivalence, such as self-reported health survey data. Differential item functioning (DIF) analysis is crucial for evaluating measurement …

Health-related quality of life (HRQoL) is a multidimensional concept that encompasses the physical, mental, and social aspects of health [ 1 ]. Lower HRQoL levels, closely associated with increased risks of conditions like obesity/overweight …

In this review, we explore the instructions provided to informal carers (‘proxies’) completing questionnaires for individuals who are unable to complete questionnaires. By understanding these instructions, informal carers can provide useful …

Irritable bowel syndrome (IBS) affects 10–15% of the global population [ 1 ]. It is a functional gastrointestinal disorder characterized by abdominal pain, bloating, and altered bowel habits. These symptoms significantly affect patients’ quality of …

Patients with cancer worldwide often face considerable financial burdens [ 1 ]. The experienced financial challenges can adversely impact their financial well-being, which is the perceived ability to sustain living standards and achieve financial …

Adolescents and young adults (AYAs) are defined as individuals aged between 15 and 39 years at the time of their initial cancer diagnosis, according to the US National Cancer Institute [ 1 ]. However, the AYA age range may be defined differently in …

This study employed a well-established methodology, as described by Kisala and Tulsky [ 42 ], for identifying important HRQOL topics for rehabilitation populations, which utilizes open-ended and free-flowing discussion of the experiences of …

Thresholds for meaningful within-individual change (MWIC) are crucial for interpreting patient-reported outcomes (PRO) data and evaluating treatment benefits. Traditional methods for determining MWIC threshold can be biased, especially when the …

There is a renewed interest in measuring the health-related quality of life of people with long-standing diseases because it measures the effect of diseases on regular activities and functions. This concept has been studied among people with …

Colorectal cancer (CRC) poses significant health challenges globally and remains a predominant cancer type in Portugal, where it is the second leading cause of cancer-related deaths [ 1 ]. Advancements in medical science have improved survival …

Cancer is one of the leading causes of death and continues to impact the lives of millions worldwide profoundly. Historically, the primary focus of cancer treatment has been overall survival or progression-free survival [ 1 ]. However …

Serious injuries or illnesses can severely compromise one’s quality of life, increase the strains on one’s caregivers and put one at high risk of death [ 1 ]. Such health conditions, whether chronic or acute, often require immediate treatment as an …

Approximately 3,700 ostomy surgeries are performed annually in Norway [ 1 ] due to conditions such as cancer, inflammatory bowel diseases (IBD), congenital abnormalities, and several other diagnoses [ 2 ]. An ostomy diverts urine or faeces to an …

Health-related quality of life (HRQoL) is an important outcome of health care, reflecting individuals’ subjective evaluations of their health [ 1 , 2 ]. Measuring HRQoL is crucial for understanding patient health [ 1 , 3 ] and evaluating healthcare …

Kinesiophobia (fear of movement) refers to the excessive and irrational fear of exercise or physical activity(PA) due to the perceived risk of injury or re-injury [ 1 ]. The fear may lead to PA avoidance, resulting in deconditioning, muscle …

The rising life expectancy, mostly driven by advancements in medical technology, is contributing to a growing global population of older adults aged 65 years and over [ 1 , 2 ]. By 2066, the proportion of Australians aged 65 years or over is …