Objectives
This study examined the effect of mindfulness-based intervention (MBI) on pain and quality of sleep (QoS) in patients with end-stage renal disease (ESRD) undergoing hemodialysis.
Method
An experimental, repeated measures, parallel control, randomized design was implemented among 60 patients with ESRD (PwESRD) undergoing hemodialysis from April to August 2023 in a hemodialysis unit. Simple random assignment created two equal experimental and control groups (n = 30 each). The experimental group received MBI in addition to hemodialysis, practicing three half-hour sessions per week for 5 weeks. Control group patients received hemodialysis treatment as usual, with three hemodialysis sessions for 5 weeks without any additional intervention. The study variables (pain and QoS) were measured for both groups at the outset, 2 weeks after commencing the intervention, and 5 weeks after initiation. Variables were measured by the Numeric Pain Rating Scale (NPRS) and the Pittsburgh Sleep Quality Index (PSQI) questionnaire. Repeated measures analysis of variance (RM-ANOVA) was used to analyze the main study data.
Results
The mixed-model repeated measures ANOVAs revealed that, compared to the control group, the experimental group showed lower levels of pain (p-value for the group × time interaction < 0.001) and higher levels of QoS (p-value for the group × time interaction < 0.001) over time.
Conclusions
The encouraging results arising from this research support the deployment of MBI by policymakers as a cost-effective evidence-based practice for patients undergoing hemodialysis, particularly to reduce pain and improve QoS.
Preregistration
CinicalTrials.gov, Identifier: NCT06064994.