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Gepubliceerd in:

31-08-2024

Socio-cognitive facilitators of ART-adherence among predominantly black sexual and gender minoritized persons living with HIV in Atlanta, Georgia: a latent profile analysis

Auteurs: John Mark Wiginton, Lisa A. Eaton, Valeria A. Earnshaw, Ryan J. Watson, Seth C. Kalichman

Gepubliceerd in: Journal of Behavioral Medicine | Uitgave 6/2024

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Abstract

The Integrated Change Model describes several social and cognitive factors (e.g., health attitudes, social support, self-efficacy) that can affect medication adherence. Guided by this model, we sought to identify profiles of socio-cognitive facilitators of ART (antiretroviral therapy) adherence among diversely minoritized persons living with HIV enrolled in a behavioral intervention trial in Atlanta, Georgia (N = 477). To do this, we performed latent profile analysis on baseline responses to scales assessing 6 indicators of interest: HIV-care self-efficacy, social support, TasP (treatment-as-prevention) beliefs, trust in healthcare providers, perceived need for ART, and trust in ART. We regressed emergent profiles on internalized, enacted, and microaggressive HIV stigma and compared prospective 30-day ART adherence and several cross-sectional HIV outcomes across profiles. Mean age was 29 years; 83% of participants were non-Hispanic Black, 53% were gay/homosexual-identifying, and 12% were gender expansive. Three profiles emerged: “Constrained/Capable” (6%), featuring high self-efficacy but low-moderate provider trust, social support, TasP beliefs, ART trust, and ART need; “Conflicted” (13%), featuring high TasP beliefs, provider trust, and ART need but moderate self-efficacy, ART trust, and social support; and “Motivated” (81%), featuring high levels of all indicators. Greater internalized, enacted, and microaggressive stigma were positively associated with “Conflicted” relative to “Motivated” profile membership. ART-nonadherence, unsuppressed viral load, and viral load unawareness were more likely for the “Conflicted” relative to the “Motivated” profile. Personalized HIV care tailored to such profiles may improve ART adherence and related outcomes for minoritized persons living with HIV.
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Metagegevens
Titel
Socio-cognitive facilitators of ART-adherence among predominantly black sexual and gender minoritized persons living with HIV in Atlanta, Georgia: a latent profile analysis
Auteurs
John Mark Wiginton
Lisa A. Eaton
Valeria A. Earnshaw
Ryan J. Watson
Seth C. Kalichman
Publicatiedatum
31-08-2024
Uitgeverij
Springer US
Gepubliceerd in
Journal of Behavioral Medicine / Uitgave 6/2024
Print ISSN: 0160-7715
Elektronisch ISSN: 1573-3521
DOI
https://doi.org/10.1007/s10865-024-00510-5