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Research on Child and Adolescent Psychopathology
Gepubliceerd in:

01-08-2011

Serotonin Transporter Genotype Moderates the Link Between Children’s Reports of Overprotective Parenting and Their Behavioral Inhibition

Auteurs: Katie L. Burkhouse, Brandon E. Gibb, Meredith E. Coles, Valerie S. Knopik, John E. McGeary

Gepubliceerd in: Research on Child and Adolescent Psychopathology | Uitgave 6/2011

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Abstract

The goal of the current study was to examine environmental and genetic correlates of children’s levels of behavioral inhibition (BI). Participants were 100 mother child pairs drawn from the community who were part of a larger study of the intergenerational transmission of depression. Results indicated that higher levels of maternal overprotection, as reported by the child, were associated with elevations in BI among children carrying two copies of the lower expressing 5-HTTLPR alleles (S or LG), but not among those carrying only one copy or those homozygous for the LA allele. In addition, this interaction was specific for the social component of BI, not the nonsocial component. This relation was maintained even after statistically controlling for children’s and mother’s psychopathology. Together, these findings add to emerging research demonstrating that G × E interactions predict variation in BI during childhood.
vorige artikel Association of ADAM10 and CAMK2A Polymorphisms with Conduct Disorder: Evidence from Family-Based Studies
volgende artikel Unpacking Links between Fathers’ Antisocial Behaviors and Children’s Behavior Problems: Direct, Indirect, and Interactive Effects
Voetnoten
1
Details of these analyses are available from the first author.
 
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Metagegevens
Titel
Serotonin Transporter Genotype Moderates the Link Between Children’s Reports of Overprotective Parenting and Their Behavioral Inhibition
Auteurs
Katie L. Burkhouse
Brandon E. Gibb
Meredith E. Coles
Valerie S. Knopik
John E. McGeary
Publicatiedatum
01-08-2011
Uitgeverij
Springer US
Gepubliceerd in
Research on Child and Adolescent Psychopathology / Uitgave 6/2011
Print ISSN: 2730-7166
Elektronisch ISSN: 2730-7174
DOI
https://doi.org/10.1007/s10802-011-9526-2

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