Skip to main content
Mijn bibliotheek
Ga naar:
Nieuws Boeken Tijdschriften Toetsvragen Web-tv Video Audio
Tips voor Mijn BSL
BSL Shop
Inloggen

Welkom bij Erasmus MC & Bohn Stafleu van Loghum

Erasmus MC heeft ervoor gezorgd dat je Mijn BSL eenvoudig en snel kunt raadplegen. Je kunt je links eenvoudig registreren. Met deze gegevens kun je thuis, of waar ook ter wereld toegang krijgen tot Mijn BSL.

» Andere revante producten voor Erasmus MC studenten en medewerkers.

Registreer

Om ook buiten de locaties van Erasmus MC, thuis bijvoorbeeld, van Mijn BSL gebruik te kunnen maken, moet je jezelf eenmalig registreren. Dit kan alleen vanaf een computer op een van de locaties van Erasmus MC.

Eenmaal geregistreerd kun je thuis of waar ook ter wereld onbeperkt toegang krijgen tot Mijn BSL.

Login

Als u al geregistreerd bent, hoeft u alleen maar in te loggen om onbeperkt toegang te krijgen tot Mijn BSL.

Inloggen
Top
Journal of Autism and Developmental Disorders
Gepubliceerd in:

01-06-2012 | Original Paper

Valence Scaling of Dynamic Facial Expressions is Altered in High-Functioning Subjects with Autism Spectrum Disorders: an fMRI Study

Auteurs: Jukka S. Rahko, Jyri-Johan Paakki, Tuomo H. Starck, Juha Nikkinen, David L. Pauls, Jari V. Kätsyri, Eira M. Jansson-Verkasalo, Alice S. Carter, Tuula M. Hurtig, Marja-Leena Mattila, Katja K. Jussila, Jukka J. Remes, Sanna A. Kuusikko-Gauffin, Mikko E. Sams, Sven Bölte, Hanna E. Ebeling, Irma K. Moilanen, Osmo Tervonen, Vesa Kiviniemi

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 6/2012

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail
    Link delen
publish
Publiceer nu

Abstract

FMRI was performed with the dynamic facial expressions fear and happiness. This was done to detect differences in valence processing between 25 subjects with autism spectrum disorders (ASDs) and 27 typically developing controls. Valence scaling was abnormal in ASDs. Positive valence induces lower deactivation and abnormally strong activity in ASD in multiple regions. Negative valence increased deactivation in visual areas in subjects with ASDs. The most marked differences between valences focus on fronto-insular and temporal regions. This supports the idea that subjects with ASDs may have difficulty in passive processing of the salience and mirroring of expressions. When the valence scaling of brain activity fails, in contrast to controls, these areas activate and/or deactivate inappropriately during facial stimuli presented dynamically.
vorige artikel Measuring Reciprocity in High Functioning Children and Adolescents with Autism Spectrum Disorders
volgende artikel Evidence-Based Social Skills Training for Adolescents with Autism Spectrum Disorders: The UCLA PEERS Program
Bijlagen
Alleen toegankelijk voor geautoriseerde gebruikers
Literatuur
Adolphs, R. (2002). Recognizing emotion from facial expressions: Psychological and neurological mechanisms. Behavioral and Cognitive Neuroscience Reviews, 1, 21–62.PubMedCrossRef
Adrien, J. L., Perrot, A., Sauvage, D., Leddet, I., Larmande, C., Hameury, L., et al. (1992). Early symptoms in autism from family home movies. Evaluation and comparison between 1st and 2nd year of life using I.B.S.E. scale. Acta Paedopsychiatrica, 55(2), 71–75.PubMed
Adrien, J. L., Lenoir, P., Martineau, J., Perrot, A., Hameury, L., Larmande, L., et al. (1993). Blind ratings of early symptoms of autism based upon family home movies. Journal of the American Academy of Child and Adolescent Psychiatry, 32(3), 617–626.PubMedCrossRef
American Psychiatric Association (APA). (2000). Diagnostic and statistical manual of mental disorders: DSM-IV-TR (fourth edition, text revision). Washington, DC: American Psychiatric Association.CrossRef
Baranek, G. T. (1999). Autism during Infancy: A retrospective video analysis of sensory-motor and social behaviors at 9–12 months of age. Journal of Autism and Developmental Disorders, 29(3), 213–224.PubMedCrossRef
Behrmann, M., Cibu, T., & Humphreys, K. (2006). Seeing it differently: Visual processing in autism. Trends in Cognitive Sciences, 10(6), 259–264.CrossRef
Best, C. T., Womer, J. S., & Queen, H. F. (1994). Hemispheric asymmetries in adults’ perception of infant emotional expressioins. Journal of Experimental Psychology Human Perc Performance, 20, 751–765.CrossRef
Caron, M.-J., Mottron, L., Berthiaume, C., & Dawson, M. (2006). Cognitive mechanism, specificity and neural underpinnings of visuo-spatial peaks in autism. Brain, 129, 1789–1802.PubMedCrossRef
Dahlgren, S. O., & Gillberg, C. (1989). Symptoms in the first two years of life. A preliminary population study of infantile autism. European Archives of Psychology and Neurological Sciences, 238, 169–174.CrossRef
Dapretto, M., Davies, M. S., Pfeifer, J. H., Scott, A. A., Sigman, M., Bookheimer, S. Y., et al. (2006). Understanding emotions in others: Mirror neuron dysfunction in children with autism spectrum disorders. Natural Neuroscience, 9(1), 28–30.CrossRef
Davidson, R. J., & Irwin, W. (1999). The functional neuroanatomy of emotion and affective style. Trends in cognitive sciences, 3(1), 11–21.PubMedCrossRef
De Vignemont, F., & Singer, T. (2006). The empathic brain: How, when and why? Trends in Cognitive Science, 10(10), 435–441.CrossRef
Deruelle, C., Hubert, B., Santos, A., & Wicker, B. (2008). Negative emotion does enhance recall skills in adults with autistic spectrum disorders. Autism Research, 1(2), 91–99.PubMedCrossRef
Dinstein, I., Thomas, C., Behrmann, M., & Heeger, D. J. (2008). A mirror up to nature. Current Biology, 18(1), 13–18.CrossRef
Ehlers, S., Gillberg, C., & Wing, L. (1999). A screening guestionnaire for asperger syndrome and other high-functioning autism spectrum disorders in school age children. Journal of Autism and Developmental Disorders, 29(2), 129–141.PubMedCrossRef
Ekman, P., & Friesen, W. V. (1978). Pictures of facial affect. Palo Alto, CA: Consulting Psychologist Press.
Gopnik, A., & Meltzoff, A. N. (1994). Minds, bodies and persons: Young children’s understanding of the self and others as reflected in imitation and “theory of mind” research. In S. Parker & R. Mitchell (Eds.), Self-awareness in animals and humans. New York: Cambridge University Press.
Hadjikhani, N., Joseph, R. M., Snyder, J., & Tager-Flusberg, H. (2006). Anatomical differences in the mirror neuron system and social cognition network in autism. Cerebral Cortex, 16(9), 1276–1282.PubMedCrossRef
Hadjikhani, N., Joseph, R. M., Snyder, J., & Tager-Flusberg, H. (2007). Abnormal activation of the social brain during face perception in autism. Human Brain Mapping, 28(5), 441–449.PubMedCrossRef
Iacoboni, M. (2005). Neural mechanisms of imitation. Current Opinion in Neurobiology, 15(6), 632–637.PubMedCrossRef
Iacoboni, M., Woods, R. P., Brass, B., Bekkering, H., Mazziotta, J. C., & Rizzolatti, G. (1999). Cortical mechanisms of human imitation. Science, 286(5449), 2526–2528.PubMedCrossRef
Jansson-Verkasalo, E., Kujala, T., Jussila, K., Mattila, M.-L., Moilanen, I., Näätänen, R., et al. (2005). Similarities in the phenotype of the auditory neural substrate in children with Asperger syndrome and their parents. European Journal of Neuroscience, 22(4), 986–990.PubMedCrossRef
Jenkinson, M., & Smith, S. M. (2001). A Global optimisation method for robust affine registration of brain images. Medical Image Analysis, 5(2), 143–156.PubMedCrossRef
Jenkinson, M., Bannister, P., Brady, M., & Smith, S. M. (2002). Improved optimization for the robust and accurate linear registration and motion correction of brain images. Neuroimage, 17, 825–841.PubMedCrossRef
Johnson, M. H., Griffin, R., Csibra, G., Halit, H., Farroni, T., de Haan, M., et al. (2005). The emergence of the social brain network: Evidence from typical and atypical development. Development and Psychopathology, 17, 599–619.PubMedCrossRef
Johnson-Frey, S., Maloof, F., Newman-Norlund, R., Farrer, C., Inati, S., & Grafton, S. (2003). Actions or hand-object interactions human inferior frontal cortex and action observation. Neuron, 39(6), 1053–1058.PubMedCrossRef
Joseph, R. M., & Tanaka, J. (2003). Holistic and part-based face recognition in children with autism. Journal of Autism and Developmental Disorders, 34, 199–210.
Kadesjo, B., Gillberg, C., & Hagberg, B. (1999). Brief report: Autism and Asperger syndrome in seven-year-old children: A total population study. Journal of Autism and Developmental Disorders, 29, 327–331.PubMedCrossRef
Kätsyri J. (2006). Human Recognition of Basic Emotions from Posed and Animated Dynamic Facial Expressions. Helsinki University of Technology. Dissertation in PDF format (ISBN 951-22-8538-X).
Kaufman, J., Birmaher, B., Brent, D., Rao, U., Flynn, C., Moreci, P., et al. (1997). Schedule for affective disorders and schizophrenia for school-age children-present and lifetime version (K-SADS-PL): Initial reliability and validity data. Journal of the American Academy of Child and Adolescent Psychiatry, 36(7), 980–988.PubMedCrossRef
Kennedy, D. P., Redcay, E., & Courchesne, E. (2006). Failing to deactivate: Resting functional abnormalities in autism. PNAS, 103(21), 8275–8280.PubMedCrossRef
Kientz, M. A., & Dunn, W. (1997). A comparison of the performance of children with and without autism on the sensory profile. American Journal of Occupational Therapy, 51(7), 530–537.PubMedCrossRef
Kuusikko, S., Pollock-Wurman, R., Jussila, K., Carter, A. S., Mattila, M. L., Ebeling, H., et al. (2008). Social anxiety in high-functioning children and adolescents with autism and asperger syndrome. Journal of Autism and Developmental Disorders, 38(9), 1697–1709.PubMedCrossRef
Kuusikko, S., Haapsamo, H., Jansson-Verkasalo, E., Hurtig, T., Mattila, M. L., Ebeling, H., et al. (2009). Emotion recognition in children and adolescents with autism spectrum disorders. Journal of Autism and Developmental Disorders, 39(6), 938–945.PubMedCrossRef
LaBar, K. S., Crupain, M. J., Voyvodic, J. T., & McCarthy, G. (2003). Dynamic perception of facial affect and identity in the human brain. Cerebral Cortex, 13(10), 1023–1033.PubMedCrossRef
Lord, C., Rutter, M., & LeCouteur, A. (1995). Autism diagnostic interview–revised (3rd ed.). Los Angeles: Western psychological services.
Lord, C., Rutter, M., DiLavore, P. C., & Risi, S. (2000). Autism diagnostic observation schedule (ADOS). Los Angeles: Western Psychological Services.
Mattila, M. L., Kielinen, M., Jussila, K., Linna, S. L., Bloigu, R., Ebeling, H., et al. (2007). An epidemiological and diagnostic study of Asperger syndrome according to four sets of diagnostic criteria. Journal of the American Academy of Child and Adolescent Psychiatry, 46(5), 636–646.PubMedCrossRef
Mattila, M. L., Jussila, K., Kuusikko, S., Kielinen, M., Linna, S. L., Ebeling, H., et al. (2009). When does the autism spectrum screening questionnaire (ASSQ) predict autism spectrum disorders in primary school-aged children? European Child and Adolescent Psychiatry, 18(8), 499–509.PubMedCrossRef
Mattila, M. L., Hurtig, T., Haapsamo, H., Jussila, K., Kuusikko-Gauffin, S., Kielinen, M., et al. (2010). Comorbid psychiatric disorders associated with asperger syndrome/high-functioning autism: A community- and clinic-based study. Journal of Autism and Developmental Disorders, 40(9), 1080–1093.PubMedCrossRef
Mattila, M. L., Kielinen, M., Linna, S. L., Jussila, K., Ebeling, H., Bloigu, R., et al. (2011). Autism spectrum disorders according to DSM-IV-TR and comparison with DSM-5 draft criteria: An epidemiological study. Journal of the American Academy Child and Adolescent Psychiatry, 50(6), 583–592.CrossRef
Morris, J., Ohman, A., & Dolan, R. (1998). Conscious and unconscious emotional learning in the human amygdala. Nature, 393, 467–470.PubMedCrossRef
Morris, J. S., Ohman, A., & Dolan, R. J. (1999). A subcortical pathway to the right amygdale mediating “unseen” fear. Proceedings of the National Academy of Sciences, USA, 96, 1680–1685.CrossRef
Nomura, M., Ohira, H., Haneda, K., Iidaka, T., Sadato, N., Okada, T., et al. (2004). Functional association of the amygdala and ventral prefrontal cortex during cognitive evaluation of facial expressions primed by masked angry faces: An event-related fMRI study. NeuroImage, 21(1), 352–363.PubMedCrossRef
Osterling, J., & Dawson, G. (1994). Early recognition of children with autism: A study of first birthday home videotapes. Journal of Autism and Developmental Disorder, 24, 247–257.CrossRef
Paakki, J. J., Rahko, J., Long, X., Moilanen, I., Tervonen, O., Nikkinen, J., et al. (2010). Alterations in regional homogeneity of resting-state brain activity in autism spectrum disorders. Brain Research, 1321, 169–179.PubMedCrossRef
Pelphrey, K. A., Morris, J. P., McCarthy, G., & Labar, K. L. (2007). Perception of dynamic changes in facial affect and identity in autism. Social cognitive and affective neuroscience, 2(2), 140–149.PubMedCrossRef
Pfeifer, J. H., Iacoboni, M., Mazziotta, J. C., & Dapretto, M. (2008). Mirroring others’ emotions relates to empathy and interpersonal competence in children.”. NeuroImage, 39(4), 2076–2085.PubMedCrossRef
Rahko, J., Paakki, J. J., Starck, T., Nikkinen, J., Remes, J., Hurtig, T., et al. (2010). Functional mapping of dynamic happy and fearful facial expression processing in adolescents. Brain Imaging and Behavior, 4(2), 164–176.PubMedCrossRef
Rubenstein, J. L., & Merzenich, M. M. (2003). Model of autism: Increased ratio of excitation/inhibition in key neural systems. Genes Brain Behaviour, 2, 255–267.CrossRef
Russell, J. A., & Barrett, L. F. (1999). Core affect, prototypical emotional episodes, and other things called emotion: Dissecting the elephant. Journal of Personality and Social Psychology, 76, 805–829.PubMedCrossRef
Sato, W., & Aoki, S. (2006). Right hemispheric dominance in processing of unconscious negative emotion. Brain Cognitive, 62(3), 261–266.CrossRef
Sato, W., Kochiyama, T., Yoshikawa, S., Naito, E., & Matsumura, M. (2004). Enhanced neural activity in response to dynamic facial expressions of emotion: An fMRI study. Cognitive Brain Research, 20, 81–91.PubMedCrossRef
Schultz, R. T., & Robert, T. (2005). Developmental deficits in social perception in autism: The role of the amygdala and fusiform face area. International Journal of Developmental Neuroscience: The Official Journal of the International Society for Developmental Neuroscience, 23(2–3), 125–141.CrossRef
Schultz, R., Gauthier, I., Klin, A., Fulbright, R., Anderson, A., Volkmar, F., et al. (2000). Abnormal ventral temporal cortical activity during face discrimination among individuals with autism and Asperger syndrome. Archives of General Psychiatry, 57, 331–340.PubMedCrossRef
Sigman, M., Dijamco, A., Gratier, M., & Rozga, A. (2004). Early detection of core deficits in autism. Mental retardation and developmental disabilities research reviews, 10(4), 221–233.PubMedCrossRef
Sridharan, D., Levitin, D. J., & Menon, V. (2008). A critical role for the right fronto-insular cortex in switching between central-executive and default-mode networks. Proceedings of the National Academy of Sciences of the United States of America, 105(34), 12569–12574.PubMedCrossRef
Stroop, J. (1935). Studies of interference in serial-verbal reaction. Journal of Experimental Psychology, 18, 643–662.CrossRef
Talairach, J., & Tournoux, P. (1998). Co-planar stereotaxic atlas of the human brain. Stuttgart: Thieme, 122.
Teunisse, J. P., & de Gelder, B. (2003). Face processing in adolecents with autistic disorder: The inversion and composite effects. Brain Cognitive, 52, 285–294.CrossRef
Trautmann, S. A., Fehr, T., & Herrmann, M. (2009). Emotions in motion: Dynamic compared to static facial expressions of disgust and happiness reveal more widespread emotion-specific activations. Brain Research, 1284, 100–115.PubMedCrossRef
Uddin, L. Q., & Menon, V. (2009). The anterior insula in autism: Under-connected and under-examined. Neuroscience and Biobehavioral Reviews, 33(8), 1198–1203.PubMedCrossRef
Uddin, L. Q., Davies, M. S., Scott, A. A., Zaidel, E., Bookheimer, S. Y., Iacoboni, M., et al. (2008). Neural basis of self and other representation in autism: An fMRI study of self-face recognition. PLoS One, 3(10), e3526.PubMedCrossRef
Viinikainen, M., Jääskeläinen, I. P., Alexandrov, Y., Balk, M. H., Autti, T., & Sams, M. (2010). Nonlinear relationship between emotional valence and brain activity: Evidence of separate negative and positive valence dimensions. Human Brain Mapping, 31(7), 1030–1040. URL: http://​dx.​doi.​org/​10.​1002/​hbm.​20915.
Wechsler, D. (1991). Wechsler intelligence scale for children (WISC-III) (3rd ed.). New York: The Psychological Corporation.
Weiss, L. A., Arking, D. E., Gene Discovery Project of Johns Hopkins, the Autism Consortium, Daly, M., & Chakravarti, A. (2009). A genome-wide linkage and association scan reveals novel loci for autism. Nature, 461(7265), 802–808.PubMedCrossRef
Wicker, B., Keysers, C., Plailly, J., Royet, J. P., Gallese, V., & Rizzolatti, G. (2003). Both of us disgusted in My insula: The common neural basis of seeing and feeling disgust. Neuron, 40(3), 655–664.PubMedCrossRef
Woolrich, M. W., Behrens, T. E. J., Beckmann, C. F., Jenkinson, M., & Smith, S. M. (2004). Multilevel linear modelling for FMRI group analysis using Bayesian inference. NeuroImage, 21(4), 1732–1747.PubMedCrossRef
Metagegevens
Titel
Valence Scaling of Dynamic Facial Expressions is Altered in High-Functioning Subjects with Autism Spectrum Disorders: an fMRI Study
Auteurs
Jukka S. Rahko
Jyri-Johan Paakki
Tuomo H. Starck
Juha Nikkinen
David L. Pauls
Jari V. Kätsyri
Eira M. Jansson-Verkasalo
Alice S. Carter
Tuula M. Hurtig
Marja-Leena Mattila
Katja K. Jussila
Jukka J. Remes
Sanna A. Kuusikko-Gauffin
Mikko E. Sams
Sven Bölte
Hanna E. Ebeling
Irma K. Moilanen
Osmo Tervonen
Vesa Kiviniemi
Publicatiedatum
01-06-2012
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 6/2012
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-011-1332-8

Andere artikelen Uitgave 6/2012

Brief Report: The Assessment of Anxiety in High-Functioning Adolescents with Autism Spectrum Disorder

  • Brief Report

Psychotropic Medications in Autism: Practical Considerations for Parents

  • Original Paper

Applying Technology to Visually Support Language and Communication in Individuals with Autism Spectrum Disorders

  • Original Paper

Postural Hypo-Reactivity in Autism is Contingent on Development and Visual Environment: A Fully Immersive Virtual Reality Study

  • Open Access

Brief Report: Consistency of Search Engine Rankings for Autism Websites

  • Brief Report

Adaptive Response of Children and Adolescents with Autism to the 2009 Earthquake in L’Aquila, Italy

  • Open Access
  • Original paper