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Gepubliceerd in:

30-06-2020

Exploring health-related quality of life and frailty in older adults based on the Korean Frailty and Aging Cohort Study

Auteurs: Moon Jung Kim, Saengryeol Park, Young-il Jung, Seon-Ha Kim, In-Hwan Oh

Gepubliceerd in: Quality of Life Research | Uitgave 11/2020

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Abstract

Purpose

The study aimed to analyze the association between frailty and health-related quality of life (HRQOL) based on the Korean Frailty and Aging Cohort Study.

Methods

In this cross-sectional study, 2905 adults aged 70 to 84 years were enrolled. Frailty was determined according to the Fried frailty index. HRQOL was measured using the 5-level EuroQol questionnaire (EQ-5D-5L) and the 12-item Short-Form Health Survey version 2 (SF-12). Hierarchical linear regressions were conducted to examine the relationship between frailty and HRQOL and a logistic regression analysis was performed to estimate odds ratios of frailty status in the scores of the lowest quartiles in each scale.

Results

Of the total respondents, 7.8% were frail, 47.0% were pre-frail, and 45.2% were robust. Frail respondents had significantly lower HRQOL scores than robust respondents, especially for EQ-5D-5L utility weights (0.74 vs 0.93). Frailty was strongly associated with decreased HRQOL in both physical and mental component summary of SF-12 (p < 0.001). Both pre-frail and frail states were related to greater odds of scoring in the bottom 25% of HRQOL scales compared to the non-frail state (p < 0.0001).

Conclusion

Frailty was associated with declined HRQOL in Korean older adults. This result recommends raising awareness about identifying and preventing frailty for better quality of life in the Korean elderly population.

Literatuur
  1. Fried, L. P., Tangen, C. M., Walston, J., Newman, A. B., Hirsch, C., Gottdiener, J., et al. (2001). Frailty in older adults: Evidence for a phenotype. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 56(3), M146–M157.View Article
  2. Fried, L. P., Ferrucci, L., Darer, J., Williamson, J. D., & Anderson, G. (2004). Untangling the concepts of disability, frailty, and comorbidity: Implications for improved targeting and care. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 59(3), 255–263.View Article
  3. Strandberg, T. E., Pitkälä, K. H., & Tilvis, R. S. (2011). Frailty in older people. European Geriatric Medicine, 2(6), 344–355.View Article
  4. Hébert, R. (1997). Functional decline in old age. Canadian Medical Association Journal, 157(8), 1037–1045.
  5. Benyamini, Y., Idler, E. L., Leventhal, H., & Leventhal, E. A. (2000). Positive affect and function as influences on self-assessments of health: Expanding our view beyond illness and disability. The Journals of Gerontology Series B: Psychological Sciences and Social Sciences, 55(2), P107–P116.View Article
  6. Hays, R. D., & Reeve, B. B. (2010). Measurement and modeling of health-related quality of life. In J. Killewo, H. K. Heggenhougen, & S. R. Quah (Eds.), Epidemiology and demography in public health (pp. 195–205). San Diego: Academic Press.
  7. Gold, M. R., Patrick, D. L., Torrance, G. W., Fryback, D., Hadorn, D. C., Kamlet, M., et al. (1996). Identifying and valuing outcomes. In M. R. Gold, J. E. Siegel, L. B. Russell, & M. C. Weinstein (Eds.), Cost-effectiveness in health and medicine. Oxford: Oxford University Press.
  8. Karimi, M., & Brazier, J. (2016). Health, health-related quality of life, and quality of life: What is the difference? Pharmacoeconomics, 34(7), 645–649.View Article
  9. Higginson, I. J., & Carr, A. J. (2001). Measuring quality of life: Using quality of life measures in the clinical setting. BMJ, 322(7297), 1297–1300.View ArticlePubMed Central
  10. Browne, J. P., O’Boyle, C. A., McGee, H. M., Joyce, B., McDonald, N. J., O’Malley, K., et al. (1994). Individual quality of life in the healthy elderly. Quality of Life Research, 3, 235–244. https://​doi.​org/​10.​1007/​BF00434897.View Article
  11. Dolan, P. (2000). The measurement of health-related quality of life for use in resource allocation decisions in health care. In A. Culyer & J. P. Newhouse (Eds.), Handbook of health economics (pp. 1723–1760). Washington, DC: Elsevier. https://​doi.​org/​10.​1016/​s1574-0064(00)80045-1.View Article
  12. Won, C. W., Lee, Y., Choi, J., Kim, K. W., Park, Y., Park, H., et al. (2016). Starting construction of frailty cohort for elderly and intervention study. Annals of Geriatric Medicine and Research, 20(3), 114–117.View Article
  13. Kim, K. J., Shin, J., Choi, J., & Won, C. W. (2018). Discrepancies in the prevalence of known frailty scales: Korean Frailty and Aging Cohort Study. Annals of Geriatric Medicine and Research, 22(3), 137–144.View ArticlePubMed Central
  14. Won, C. W., Lee, S., Kim, J., Chon, D., Kim, S., Kim, C., et al. (2020). Korean frailty and aging cohort study (KFACS): Cohort profile. British Medical Journal Open, 10(4), e035573.
  15. Kim, H. J., Park, S., Park, S. H., Heo, Y. W., Chang, B. S., Lee, C. K., et al. (2017). The significance of frailty in the relationship between socioeconomic status and health-related quality of life in the Korean community-dwelling elderly population: Mediation analysis with bootstrapping. Quality of Life Research, 26(12), 3323–3330.View ArticlePubMed Central
  16. Lee, S. J., Son, H., & Shin, S. K. (2015). Influence of frailty on health-related quality of life in pre-dialysis patients with chronic kidney disease in Korea: A cross-sectional study. Health and Quality of Life Outcomes, 13(1), 1–7.View Article
  17. Masel, M. C., Graham, J. E., Reistetter, T. A., Markides, K. S., & Ottenbacher, K. J. (2009). Frailty and health related quality of life in older Mexican Americans. Health and Quality of Life Outcomes, 7(1), 70.View ArticlePubMed Central
  18. Chang, Y. W., Chen, W. L., Lin, F. G., Fang, W. H., Yen, M. Y., Hsieh, C. C., et al. (2012). Frailty and its impact on health-related quality of life: A cross-sectional study on elder community-dwelling preventive health service users. PLoS ONE, 7(5), 1–5.
  19. Lin, C. C., Li, C. I., Chang, C. K., Liu, C. S., Lin, C. H., Meng, N. H., et al. (2011). Reduced health-related quality of life in elders with frailty: A cross-sectional study of community-dwelling elders in Taiwan. PLoS ONE, 6(7), 1–7.
  20. Kim, S. H., Ahn, J., Ock, M., Shin, S., Park, J., Luo, N., et al. (2016). The EQ-5D-5L valuation study in Korea. Quality of Life Research, 25(7), 1845–1852.View Article
  21. Garratt, A., Schmidt, L., Mackintosh, A., & Fitzpatrick, R. (2002). Quality of life measurement: Bibliographic study of patient assessed health outcome measures. BMJ: British Medical Journal, 324(7351), 1417–1419.View Article
  22. Yang, F., Devlin, N., & Luo, N. (2019). Cost-utility analysis using EQ-5D-5L data: Does how the utilities are derived matter? Value in Health, 22(1), 45–49.View Article
  23. Ware, J. (1996). A 12-item short-form health survey: Construction of scales and preliminary tests of reliability and validity. Medical Care, 34(3), 220–233.View Article
  24. Dent, E., Lien, C., Lim, W. S., Wong, W. C., Wong, C. H., Ng, T. P., et al. (2017). The Asia-Pacific clinical practice guidelines for the management of frailty. Journal of the American Medical Directors Association, 18(7), 564–575.View Article
  25. Choi, J., Ahn, A., Kim, S., & Won, C. W. (2015). Global prevalence of physical frailty by Fried’s criteria in community-dwelling elderly with national population-based surveys. Journal of the American Medical Directors Association, 16(7), 548–550.View Article
  26. Jung, H. W., Kim, S. W., Ahn, S., Lim, J. Y., Han, J. W., Kim, K. W., et al. (2014). Prevalence and outcomes of frailty in Korean elderly population: Comparisons of a multidimensional frailty index with two phenotype models. PLoS ONE, 9, e87958.View ArticlePubMed Central
  27. Son, J. H., Kim, S. Y., Won, C. W., Choi, H. R., Kim, B. S., & Park, M. S. (2015). Physical frailty predicts medical expenses in community-dwelling, elderly patients: Three-year prospective findings from living profiles of older people surveys in Korea. European Geriatric Medicine, 6, 412–416. https://​doi.​org/​10.​1016/​j.​eurger.​2015.​05.​003.View Article
  28. Kim, S. H., Jo, M. W., Ahn, J., Ock, M., Shin, S., & Park, J. (2014). Assessment of psychometric properties of the Korean SF-12 v2 in the general population. BMC Public Health, 14(1), 1086.View ArticlePubMed Central
  29. Ware, J. E., Kosinski, M., & Keller, S. D. (1995). How to score the SF12 physical and mental health summary scales. Boston, MA: The Health Institute, New England Medical Center.
  30. Brazier, J. E., & Roberts, J. (2004). The estimation of a preference-based measure of health from the SF-12. Medical Care, 42(9), 851–859.View Article
  31. Groessl, E. J., Kaplan, R. M., Rejeski, W. J., Katula, J. A., King, A. C., Frierson, G., et al. (2007). Health-related quality of life in older adults at risk for disability. American Journal of Preventive Medicine, 33(3), 214–218.View ArticlePubMed Central
  32. Heyworth, I. T., Hazell, M. L., Linehan, M. F., & Frank, T. L. (2009). How do common chronic conditions affect health-related quality of life? British Journal of General Practice, 59(568), e353–e358.View Article
  33. Chon, D., Lee, Y., Kim, J., & Lee, K. E. (2018). The association between frequency of social contact and frailty in older people: Korean Frailty and Aging Cohort Study (KFACS). Journal of Korean Medical Science, 33(51), e332.View ArticlePubMed Central
  34. Cawthon, P. M., Ensrud, K. E., Laughlin, G. A., Cauley, J. A., Dam, T. T. L., Barrett-Connor, E., et al. (2009). Sex hormones and frailty in older men: The osteoporotic fractures in men (MrOS) study. The Journal of Clinical Endocrinology & Metabolism, 94(10), 3806–3815.View Article
  35. Kirby, S. E., Coleman, P. G., & Daley, D. (2004). Spirituality and well-being in frail and nonfrail older adults. The Journals of Gerontology Series B: Psychological Sciences and Social Sciences, 59(3), P123–P129.View Article
  36. Ashing-Giwa, K. T. (2005). The contextual model of HRQoL: A paradigm for expanding the HRQoL framework. Quality of Life Research, 14(2), 297–307.View Article
  37. Fried, L. P. (2016). Interventions for human frailty: Physical activity as a model. Cold Spring Harbor Perspectives in Medicine, 6(6), 1–14.View Article
  38. Li, C. M., Chen, C. Y., Li, C. Y., Wang, W. D., & Wu, S. C. (2010). The effectiveness of a comprehensive geriatric assessment intervention program for frailty in community-dwelling older people: A randomized, controlled trial. Archives of Gerontology and Geriatrics, 50(Suppl 1), S39–S42.View ArticlePubMed Central
  39. Cleemput, I. (2010). A social preference valuations set for EQ-5D health states in Flanders, Belgium. The European Journal of Health Economics, 11(2), 205–213.View Article
  40. Shimizu, U., Aoki, H., Sakagami, M., & Akazawa, K. (2018). Walking ability, anxiety and depression, significantly decrease EuroQol 5-Dimension 5-Level scores in older hemodialysis patients in Japan. Archives of Gerontology and Geriatrics, 78, 96–100.View Article
  41. Scalone, L., Ciampichini, R., Fagiuoli, S., Gardini, I., Fusco, F., Gaeta, L., et al. (2013). Comparing the performance of the standard EQ-5D 3L with the new version EQ-5D 5L in patients with chronic hepatic diseases. Quality of Life Research, 22(7), 1707–1716.View Article
  42. Mijnarends, D. M., Schols, J. M. G. A., Halfens, R. J. G., Meijers, J. M. M., Luiking, Y. C., Verlaan, S., et al. (2016). Burden-of-illness of Dutch community-dwelling older adults with sarcopenia: Health related outcomes and costs. European Geriatric Medicine, 7(3), 276–284.View Article
  43. Lamu, A. N., Chen, G., Gamst-Klaussen, T., & Olsen, J. A. (2018). Do country-specific preference weights matter in the choice of mapping algorithms? The case of mapping the Diabetes-39 onto eight country-specific EQ-5D-5L value sets. Quality of Life Research, 27(7), 1801–1814.View Article
Metagegevens
Titel
Exploring health-related quality of life and frailty in older adults based on the Korean Frailty and Aging Cohort Study
Auteurs
Moon Jung Kim
Saengryeol Park
Young-il Jung
Seon-Ha Kim
In-Hwan Oh
Publicatiedatum
30-06-2020
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 11/2020
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-020-02568-5