This study was aimed to evaluate the impact of visual pedagogy in dental check-ups and preventive practices among children with autism aged 6–12. In this randomized double-blind clinical trial, the cooperation of 40 children with autism age 6–12. The selected children were equally divided into two groups of case and control (n = 20). The obtained data were analyzed by statistical tests, including Chi square and independent t test. The results of Cochran showed a significant increase in children’s cooperation with regard to fluoride therapy in the case group by repeating the visit and training sessions (p ≤ 0.001). The findings of this study demonstrated, visual pedagogy was merely effective in the case of fluoride therapy in the case group.