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Netherlands Heart Journal
Gepubliceerd in:

01-05-2008 | original article

Characteristics of the flow velocity-pressure gradient relation in the assessment of stenoses: an in vitro study

Auteurs: K. M. J. Marques, N. Westerhof

Gepubliceerd in: Netherlands Heart Journal | Uitgave 5/2008

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Extract

The physiological assessment of coronary stenoses is clinically important. In the catheterisation laboratory, most commonly the fractional flow reserve (FFR) and coronary flow velocity reserve (CFVR) are determined, using a pressure wire or a Doppler wire, respectively.1,2 The combined measurement of coronary pressure and flow velocity determines the flow impediment caused by a coronary stenosis, independent of the state of microcirculation. Both the hyperaemic stenosis resistance (HSR) and dpv50, which is derived from the diastolic flow velocity-pressure gradient (v-dp) relation, have been found to determine the haemodynamic significance of a coronary stenosis with a high accuracy.3-6 …
vorige artikel A statement on ethics from the HEART Group
volgende artikel Progenitor cells isolated from the human heart: a potential cell source for regenerative therapy
Literatuur
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Pijls NH, Van Gelder B, Van Der Voort PH, Peels K, Bracke FA, Bonnier HJ, et al. Fractional flow reserve. A useful index to evaluate the influence of an epicardial coronary stenosis on myocardial blood flow. Circulation 1995;92:3183-93.
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Bach RG, Kern MJ. Practical coronary physiology. Clinical application of the Doppler flow velocity guide wire. Cardiol Clin 1997; 15:77-99.
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Meuwissen M, Siebes M, Chamuleau SA, Eck-Smit BL, Koch KT, de Winter RJ, et al. Hyperemic stenosis resistance index for evaluation of functional coronary lesion severity. Circulation 2002;106:441-6.
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Siebes M, Verhoeff BJ, Meuwissen M, de Winter RJ, Spaan JA, Piek JJ. Single-wire pressure and flow velocity measurement to quantify coronary stenosis hemodynamics and effects of percutaneous interventions. Circulation 2004;109:756-62.
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Marques KM, Spruijt HJ, Boer C, Westerhof N, Visser CA, Visser FC. The diastolic flow-pressure gradient relation in coronary stenoses in humans. J Am Coll Cardiol 2002;39:1630-6.
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Marques KM, van Eenige MJ, Spruijt HJ, Westerhof N, Twisk J, Visser CA, et al. The diastolic flow velocity-pressure gradient relation and dpv50 to assess the hemodynamic significance of coronary stenoses. Am J Physiol Heart Circ Physiol 2006;291:H2630-5.
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Sabbah HN, Stein PD. Hemodynamics of multiple versus single 50 percent coronary arterial stenoses. Am J Cardiol 1982;50:276-80.
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Feldman RL, Nichols WW, Pepine CJ, Conti CR. Hemodynamic effects of long and multiple coronary arterial narrowings. Chest 1978;74:280-5.
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Karayannacos PE, Talukder N, Nerem RM, Roshon S, Vasko JS. The role of multiple noncritical arterial stenoses in the pathogenesis of ischemia. J Thorac Cardiovasc Surg 1977;73:458-69.
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Gould KL, Lipscomb K. Effects of coronary stenoses on coronary flow reserve and resistance. Am J Cardiol 1974;34:48-55.
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Dodds SR, Phillips PS. The haemodynamics of multiple sequential stenoses and the criteria for a critical stenosis. Eur J Vasc Endovasc Surg 2003;26:348-53.
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Young DF, Tsai FY. Flow characteristics in models of arterial stenoses. I. Steady flow. J Biomech 1973;6:395-410.
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Doucette JW, Corl PD, Payne HM, Flynn AE, Goto M, Nassi M, et al. Validation of a Doppler guide wire for intravascular measurement of coronary artery flow velocity. Circulation 1992;85:1899-911.
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de Bruyne B, Pijls NH, Heyndrickx GR, Hodeige D, Kirkeeide R, Gould KL. Pressure-derived fractional flow reserve to assess serial epicardial stenoses: theoretical basis and animal validation. Circulation 2000;101:1840-7.
15.
Pijls NH, de Bruyne B, Bech GJ, Liistro F, Heyndrickx GR, Bonnier HJ, et al. Coronary pressure measurement to assess the hemodynamic significance of serial stenoses within one coronary artery: validation in humans. Circulation 2000;102:2371-7.
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Anderson HV, Stokes MJ, Leon M, Abu-Halawa SA, Stuart Y, Kirkeeide RL. Coronary artery flow velocity is related To lumen area and regional left ventricular mass [In Process Citation]. Circulation 2000;102:48-54.
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de Bruyne B, Pijls NH, Paulus WJ, Vantrimpont PJ, Sys SU, Heyndrickx GR. Transstenotic coronary pressure gradient measurement in humans: in vitro and in vivo evaluation of a new pressure monitoring angioplasty guide wire. J Am Coll Cardiol 1993;22:119-26.
18.
Verberne HJ, Meuwissen M, Chamuleau SA, Verhoeff BJ, Eck-Smit BL, Spaan JA, et al. Effect of simultaneous intracoronary guide wires on the predictive accuracy of functional parameters of coronary lesion severity. Am J Physiol Heart Circ Physiol 2007;292:H2349-55.
Metagegevens
Titel
Characteristics of the flow velocity-pressure gradient relation in the assessment of stenoses: an in vitro study
Auteurs
K. M. J. Marques
N. Westerhof
Publicatiedatum
01-05-2008
Uitgeverij
Bohn Stafleu van Loghum
Gepubliceerd in
Netherlands Heart Journal / Uitgave 5/2008
Print ISSN: 1568-5888
Elektronisch ISSN: 1876-6250
DOI
https://doi.org/10.1007/BF03086137

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