Fluoropyrimidine chemotherapy has been a standard therapy in a range of solid tumours for many years. The cardiovascular side effects of fluoropyrimidines have been extensively reported.
1 Capecitabine, a precursor of 5-FU, is an oral fluoropyrimidine cytotoxic agent developed with the aim of providing a more effective and less toxic alternate to 5-FU. Capecitabine has significantly less serious toxic effects than 5-FU when used alone or in combination with other cytotoxic agents
2 and cardiotoxicity is an uncommon adverse effect. …