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Journal of Autism and Developmental Disorders

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30-07-2016 | Brief Report

Brief Report: Early VEPs to Pattern-Reversal in Adolescents and Adults with Autism

Auteurs: K. Kovarski, A. Thillay, E. Houy-Durand, S. Roux, A. Bidet-Caulet, F. Bonnet-Brilhault, M. Batty

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 10/2016

Abstract

Autism spectrum disorder (ASD) is characterized by atypical visual perception both in the social and nonsocial domain. In order to measure a reliable visual response, visual evoked potentials were recorded during a passive pattern-reversal stimulation in adolescents and adults with and without ASD. While the present results show the same age-related changes in both autistic and non-autistic groups, they reveal a smaller P100 amplitude in the ASD group compared to controls. These results confirm that early visual responses are affected in ASD even with a simple, non social and passive stimulation and suggest that they should be considered in order to better understand higher-level processes.

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In this article, we have used N75, P100 and N135 to refer to the visual evoked potentials evoked by pattern reversal (Odom et al. 2010).

Aguera, P. E., Jerbi, K., Caclin, A., & Bertrand, O. (2011). ELAN: A software package for analysis and visualization of MEG, EEG, and LFP signals. Computational Intelligence and Neuroscience, 2011, 158970. doi:10.1155/2011/158970.PubMedPubMedCentralCrossRef

Allison, T., Hume, A. L., Wood, C. C., & Goff, W. R. (1984). Developmental and aging changes in somatosensory, auditory and visual evoked potentials. Electroencephalography and Clinical Neurophysiology, 58(1), 14–24.PubMedCrossRef

Allison, T., Wood, C. C., & Goff, W. R. (1983). Brain stem auditory, pattern-reversal visual, and short-latency somatosensory evoked potentials: Latencies in relation to age, sex, and brain and body size. Electroencephalography and Clinical Neurophysiology, 55(6), 619–636.PubMedCrossRef

American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (DSM-IV-TR). Washington, DC: American Psychiatric Association.

Anagnostou, E., & Taylor, M. J. (2011). Review of neuroimaging in autism spectrum disorders: What have we learned and where we go from here. Molecular Autism, 2(1), 4. doi:10.1186/2040-2392-2-4.PubMedPubMedCentralCrossRef

Bangel, K. A., Batty, M., Ye, A. X., Meaux, E., Taylor, M. J., & Doesburg, S. M. (2014). Reduced beta band connectivity during number estimation in autism. NeuroImage: Clinical, 6, 202–213. doi:10.1016/j.nicl.2014.08.020.CrossRef

Baruth, J. M., Casanova, M. F., Sears, L., & Sokhadze, E. (2010). Early-stage visual processing abnormalities in high-functioning autism spectrum disorder (ASD). Translational Neuroscience, 1(2), 177–187. doi:10.2478/v10134-010-0024-9.PubMedPubMedCentralCrossRef

Batty, M., Meaux, E., Wittemeyer, K., Roge, B., & Taylor, M. J. (2011). Early processing of emotional faces in children with autism: An event-related potential study. Journal of Experimental Child Psychology, 109(4), 430–444. doi:10.1016/j.jecp.2011.02.001.PubMedCrossRef

Belmonte, M. K., & Yurgelun-Todd, D. A. (2003). Functional anatomy of impaired selective attention and compensatory processing in autism. Cognitive Brain Research, 17(3), 651–664.PubMedCrossRef

Bentin, S., Allison, T., Puce, A., Perez, E., & McCarthy, G. (1996). Electrophysiological studies of face perception in humans. Journal of Cognitive Neuroscience, 8(6), 551–565. doi:10.1162/jocn.1996.8.6.551.PubMedPubMedCentralCrossRef

Blakemore, S. J. (2012). Imaging brain development: The adolescent brain. Neuroimage, 61(2), 397–406. doi:10.1016/j.neuroimage.2011.11.080.PubMedCrossRef

Boeschoten, M. A., Kenemans, J. L., van Engeland, H., & Kemner, C. (2007). Abnormal spatial frequency processing in high-functioning children with pervasive developmental disorder (PDD). Clinical Neurophysiology, 118(9), 2076–2088. doi:10.1016/j.clinph.2007.05.004.PubMedCrossRef

Bruneau, N., Roux, S., Adrien, J. L., & Barthelemy, C. (1999). Auditory associative cortex dysfunction in children with autism: Evidence from late auditory evoked potentials (N1 wave-T complex). Clinical Neurophysiology, 110(11), 1927–1934.PubMedCrossRef

Casanova, M. F., van Kooten, I. A., Switala, A. E., van Engeland, H., Heinsen, H., Steinbusch, H. W., et al. (2006). Minicolumnar abnormalities in autism. Acta Neuropathologica, 112(3), 287–303. doi:10.1007/s00401-006-0085-5.PubMedCrossRef

Celesia, G. G., Kaufman, D., & Cone, S. (1987). Effects of age and sex on pattern electroretinograms and visual evoked potentials. Electroencephalography and Clinical Neurophysiology, 68(3), 161–171.PubMedCrossRef

Clark, V. P., & Hillyard, S. A. (1996). Spatial selective attention affects early extrastriate but not striate components of the visual evoked potential. Journal of Cognitive Neuroscience, 8(5), 387–402. doi:10.1162/jocn.1996.8.5.387.PubMedCrossRef

Constable, P. A., Gaigg, S. B., Bowler, D. M., & Thompson, D. A. (2012). Motion and pattern cortical potentials in adults with high-functioning autism spectrum disorder. Documenta Ophthalmologica,. doi:10.1007/s10633-012-9349-7.PubMed

Courchesne, E., Campbell, K., & Solso, S. (2011). Brain growth across the life span in autism: age-specific changes in anatomical pathology. Brain Research, 1380, 138–145. doi:10.1016/j.brainres.2010.09.101.PubMedCrossRef

Deruelle, C., Rondan, C., Salle-Collemiche, X., Bastard-Rosset, D., & Da Fonseca, D. (2008). Attention to low- and high-spatial frequencies in categorizing facial identities, emotions and gender in children with autism. Brain and Cognition, 66(2), 115–123. doi:10.1016/j.bandc.2007.06.001.PubMedCrossRef

Di Russo, F., Pitzalis, S., Spitoni, G., Aprile, T., Patria, F., Spinelli, D., et al. (2005). Identification of the neural sources of the pattern-reversal VEP. Neuroimage, 24(3), 874–886. doi:10.1016/j.neuroimage.2004.09.029.PubMedCrossRef

Di Russo, F., Spinelli, D., & Morrone, M. C. (2001). Automatic gain control contrast mechanisms are modulated by attention in humans: Evidence from visual evoked potentials. Vision Research, 41(19), 2435–2447.PubMedCrossRef

Ding, Y., Martinez, A., Qu, Z., & Hillyard, S. A. (2014). Earliest stages of visual cortical processing are not modified by attentional load. Human Brain Mapping, 35(7), 3008–3024.PubMedCrossRef

Earls, H. A., Curran, T., & Mittal, V. (2016). Deficits in early stages of face processing in schizophrenia: A systematic review of the p100 component. Schizophrenia Bulletin, 42(2), 519–527. doi:10.1093/schbul/sbv096.PubMedCrossRef

Ecker, C., Marquand, A., Mourao-Miranda, J., Johnston, P., Daly, E. M., Brammer, M. J., et al. (2010). Describing the brain in autism in five dimensions–magnetic resonance imaging-assisted diagnosis of autism spectrum disorder using a multiparameter classification approach. The Journal of Neuroscience, 30(32), 10612–10623. doi:10.1523/JNEUROSCI.5413-09.2010.PubMedCrossRef

Emmerson-Hanover, R., Shearer, D. E., Creel, D. J., & Dustman, R. E. (1994). Pattern reversal evoked potentials: Gender differences and age-related changes in amplitude and latency. Electroencephalography and Clinical Neurophysiology, 92(2), 93–101.PubMedCrossRef

Frith, U. (1989). Autism: Explaining the enigma (Cognitive development). Oxford; Cambridge, MA: Basil Blackwell.

Frith, U., & Happe, F. (1994). Autism: beyond “theory of mind”. Cognition, 50(1–3), 115–132.PubMedCrossRef

Gonzalez, C. M. G., Clark, V. P., Fan, S., Luck, S. J., & Hillyard, S. A. (1994). Sources of attention-sensitive visual event-related potentials. Brain Topography, 7(1), 41–51.CrossRef

Hazen, E. P., Stornelli, J. L., O’Rourke, J. A., Koesterer, K., & McDougle, C. J. (2014). Sensory symptoms in autism spectrum disorders. Harvard Review of Psychiatry, 22(2), 112–124. doi:10.1097/01.HRP.0000445143.08773.58.PubMedCrossRef

Heinze, H. J., Luck, S. J., Mangun, G. R., & Hillyard, S. A. (1990). Visual event-related potentials index focused attention within bilateral stimulus arrays. I. Evidence for early selection. Electroencephalography and Clinical Neurophysiology, 75(6), 511–527.PubMedCrossRef

Hileman, C. M., Henderson, H., Mundy, P., Newell, L., & Jaime, M. (2011). Developmental and individual differences on the P1 and N170 ERP components in children with and without autism. Developmental Neuropsychology, 36(2), 214–236. doi:10.1080/87565641.2010.549870.PubMedPubMedCentralCrossRef

Hillyard, S. A., & Anllo-Vento, L. (1998). Event-related brain potentials in the study of visual selective attention. Proceedings of the National Academy of Sciences, 95(3), 781–787.CrossRef

Hyde, K. L., Samson, F., Evans, A. C., & Mottron, L. (2010). Neuroanatomical differences in brain areas implicated in perceptual and other core features of autism revealed by cortical thickness analysis and voxel-based morphometry. Human Brain Mapping, 31(4), 556–566. doi:10.1002/hbm.20887.PubMed

Ikeda, J., Davitt, B. V., Ultmann, M., Maxim, R., & Cruz, O. A. (2013). Brief report: Incidence of ophthalmologic disorders in children with autism. Journal of Autism and Developmental Disorders, 43(6), 1447–1451. doi:10.1007/s10803-012-1475-2.PubMedCrossRef

Itier, R. J. (2004). N170 or N1? Spatiotemporal differences between object and face processing using ERPs. Cerebral Cortex, 14(2), 132–142. doi:10.1093/cercor/bhg111.PubMedCrossRef

Jeffreys, D. A., & Axford, J. G. (1972). Source locations of pattern-specific components of human visual evoked potentials. I. Component of striate cortical origin. Experimental Brain Research, 16(1), 1–21.PubMed

Jemel, B., Mimeault, D., Saint-Amour, D., Hosein, A., & Mottron, L. (2010). VEP contrast sensitivity responses reveal reduced functional segregation of mid and high filters of visual channels in autism. Journal of Vision, 10(6), 13. doi:10.1167/10.6.13.PubMedCrossRef

Kornmeier, J., Worner, R., Riedel, A., Bach, M., & Tebartz van Elst, L. (2014). A different view on the checkerboard? Alterations in early and late visually evoked EEG potentials in Asperger observers. PLoS ONE, 9(3), e90993. doi:10.1371/journal.pone.0090993.PubMedPubMedCentralCrossRef

Kroger, A., Bletsch, A., Krick, C., Siniatchkin, M., Jarczok, T. A., Freitag, C. M., et al. (2014). Visual event-related potentials to biological motion stimuli in autism spectrum disorders. Social Cognitive and Affective Neuroscience, 9(8), 1214–1222. doi:10.1093/scan/nst103.PubMedCrossRef

Kuba, M., Kremlacek, J., Langrova, J., Kubova, Z., Szanyi, J., & Vit, F. (2012). Aging effect in pattern, motion and cognitive visual evoked potentials. Vision Research, 62, 9–16. doi:10.1016/j.visres.2012.03.014.PubMedCrossRef

Lord, C., Risi, S., Lambrecht, L., Cook, E. H, Jr., Leventhal, B. L., DiLavore, P. C., et al. (2000). The autism diagnostic observation schedule-generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30(3), 205–223.PubMedCrossRef

Lord, C., Rutter, M., & Le Couteur, A. (1994). Autism diagnostic interview-revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. Journal of Autism and Developmental Disorders, 24(5), 659–685.PubMedCrossRef

Luck, S. J., & Hillyard, S. A. (1995). The role of attention in feature detection and conjunction discrimination: An electrophysiological analysis. International Journal of Neuroscience, 80(1–4), 281–297.PubMedCrossRef

Mahajan, Y., & McArthur, G. (2012a). Maturation of auditory event-related potentials across adolescence. Hearing Research, 294(1–2), 82–94. doi:10.1016/j.heares.2012.10.005.PubMedCrossRef

Mahajan, Y., & McArthur, G. (2012b). Maturation of visual evoked potentials across adolescence. Brain and Development, 34(8), 655–666. doi:10.1016/j.braindev.2011.10.009.PubMedCrossRef

Mangun, G. R. (1995). Neural mechanisms of visual selective attention. Psychophysiology, 32(1), 4–18.PubMedCrossRef

Mangun, G. R., & Hillyard, S. A. (1990). Allocation of visual attention to spatial locations: Tradeoff functions for event-related brain potentials and detection performance. Perception and Psychophysics, 47(6), 532–550.PubMedCrossRef

Marco, E. J., Hinkley, L. B., Hill, S. S., & Nagarajan, S. S. (2011). Sensory processing in autism: A review of neurophysiologic findings. Pediatric Research, 69(5 Pt 2), 48R–54R. doi:10.1203/PDR.0b013e3182130c54.PubMedPubMedCentralCrossRef

Martinez, A., Anllo-Vento, L., Sereno, M. I., Frank, L. R., Buxton, R. B., Dubowitz, D. J., et al. (1999). Involvement of striate and extrastriate visual cortical areas in spatial attention. Nature Neuroscience, 2(4), 364–369. doi:10.1038/7274.PubMedCrossRef

Martinez, A., Di Russo, F., Anllo-Vento, L., & Hillyard, S. A. (2001a). Electrophysiological analysis of cortical mechanisms of selective attention to high and low spatial frequencies. Clinical Neurophysiology, 112(11), 1980–1998.PubMedCrossRef

Martinez, A., Di Russo, F., Anllo-Vento, L., Sereno, M. I., Buxton, R. B., & Hillyard, S. A. (2001b). Putting spatial attention on the map: Timing and localization of stimulus selection processes in striate and extrastriate visual areas. Vision Research, 41(10–11), 1437–1457.PubMedCrossRef

McCabe, K., Rich, D., Loughland, C. M., Schall, U., & Campbell, L. E. (2011). Visual scanpath abnormalities in 22q11.2 deletion syndrome: Is this a face specific deficit? Psychiatry Research, 189(2), 292–298. doi:10.1016/j.psychres.2011.06.012.PubMedCrossRef

Milne, E., Griffiths, H., Buckley, D., & Scope, A. (2009a). Vision in children and adolescents with autistic spectrum disorder: Evidence for reduced convergence. Journal of Autism and Developmental Disorders, 39(7), 965–975. doi:10.1007/s10803-009-0705-8.PubMedCrossRef

Milne, E., Scope, A., Pascalis, O., Buckley, D., & Makeig, S. (2009b). Independent component analysis reveals atypical electroencephalographic activity during visual perception in individuals with autism. Biological Psychiatry, 65(1), 22–30. doi:10.1016/j.biopsych.2008.07.017.PubMedCrossRef

Moseley, R. L., Ypma, R. J., Holt, R. J., Floris, D., Chura, L. R., Spencer, M. D., et al. (2015). Whole-brain functional hypoconnectivity as an endophenotype of autism in adolescents. NeuroImage: Clinical, 9, 140–152. doi:10.1016/j.nicl.2015.07.015.CrossRef

Moskowitz, A., & Sokol, S. (1983). Developmental changes in the human visual system as reflected by the latency of the pattern reversal VEP. Electroencephalography and Clinical Neurophysiology, 56(1), 1–15.PubMedCrossRef

Mottron, L., Dawson, M., Soulieres, I., Hubert, B., & Burack, J. (2006). Enhanced perceptual functioning in autism: An update, and eight principles of autistic perception. Journal of Autism and Developmental Disorders, 36(1), 27–43. doi:10.1007/s10803-005-0040-7.PubMedCrossRef

Mottron, L., Mineau, S., Martel, G., Bernier, C. S., Berthiaume, C., Dawson, M., et al. (2007). Lateral glances toward moving stimuli among young children with autism: Early regulation of locally oriented perception? Development and Psychopathology, 19(1), 23–36. doi:10.1017/S0954579407070022.PubMedCrossRef

Odom, J. V., Bach, M., Brigell, M., Holder, G. E., McCulloch, D. L., Tormene, A. P., et al. (2010). ISCEV standard for clinical visual evoked potentials (2009 update). Documenta Ophthalmologica, 120(1), 111–119. doi:10.1007/s10633-009-9195-4.PubMedCrossRef

Pei, F., Baldassi, S., & Norcia, A. M. (2014). Electrophysiological measures of low-level vision reveal spatial processing deficits and hemispheric asymmetry in autism spectrum disorder. Journal of Vision,. doi:10.1167/14.11.3.PubMed

Perrin, F., Pernier, J., Bertrand, O., & Echallier, J. F. (1989). Spherical splines for scalp potential and current density mapping. Electroencephalography and Clinical Neurophysiology, 72(2), 184–187.PubMedCrossRef

Poghosyan, V., & Ioannides, A. A. (2008). Attention modulates earliest responses in the primary auditory and visual cortices. Neuron, 58(5), 802–813. doi:10.1016/j.neuron.2008.04.013.PubMedCrossRef

Rauss, K. S., Pourtois, G., Vuilleumier, P., & Schwartz, S. (2009). Attentional load modifies early activity in human primary visual cortex. Human Brain Mapping, 30(5), 1723–1733. doi:10.1002/hbm.20636.PubMedCrossRef

Rauss, K., Schwartz, S., & Pourtois, G. (2011). Top-down effects on early visual processing in humans: A predictive coding framework. Neuroscience and Biobehavioral Reviews, 35(5), 1237–1253. doi:10.1016/j.neubiorev.2010.12.011.PubMedCrossRef

Rossion, B., & Caharel, S. (2011). ERP evidence for the speed of face categorization in the human brain: Disentangling the contribution of low-level visual cues from face perception. Vision Research, 51(12), 1297–1311. doi:10.1016/j.visres.2011.04.003.PubMedCrossRef

Shi, F., Wang, L., Peng, Z., Wee, C. Y., & Shen, D. (2013). Altered modular organization of structural cortical networks in children with autism. PLoS ONE, 8(5), e63131. doi:10.1371/journal.pone.0063131.PubMedPubMedCentralCrossRef

Shigihara, Y., Hoshi, H., & Zeki, S. (2016). Early visual cortical responses produced by checkerboard pattern stimulation. Neuroimage, 134, 532–539. doi:10.1016/j.neuroimage.2016.03.078.PubMedCrossRef

Simmons, D. R., Robertson, A. E., McKay, L. S., Toal, E., McAleer, P., & Pollick, F. E. (2009). Vision in autism spectrum disorders. Vision Research, 49(22), 2705–2739. doi:10.1016/j.visres.2009.08.005.PubMedCrossRef

Sutherland, A., & Crewther, D. P. (2010). Magnocellular visual evoked potential delay with high autism spectrum quotient yields a neural mechanism for altered perception. Brain, 133(Pt 7), 2089–2097. doi:10.1093/brain/awq122.PubMedCrossRef

Takarae, Y., Luna, B., Minshew, N. J., & Sweeney, J. A. (2014). Visual motion processing and visual sensorimotor control in autism. Journal of the International Neuropsychological Society, 20(1), 113–122. doi:10.1017/S1355617713001203.PubMedCrossRef

Tanaka, S., Maezawa, Y., & Kirino, E. (2013). Classification of schizophrenia patients and healthy controls using p100 event-related potentials for visual processing. Neuropsychobiology, 68(2), 71–78. doi:10.1159/000350962.PubMedCrossRef

Taylor, M. J. (2002). Non-spatial attentional effects on P1. Clinical Neurophysiology, 113(12), 1903–1908.PubMedCrossRef

Thillay, A., Roux, S., Gissot, V., Carteau-Martin, I., Knight, R. T., Bonnet-Brilhault, F., et al. (2015). Sustained attention and prediction: Distinct brain maturation trajectories during adolescence. Frontiers in Human Neuroscience, 9, 519. doi:10.3389/fnhum.2015.00519.PubMedPubMedCentralCrossRef

Tobimatsu, S., Kurita-Tashima, S., Nakayama-Hiromatsu, M., Akazawa, K., & Kato, M. (1993). Age-related changes in pattern visual evoked potentials: Differential effects of luminance, contrast and check size. Electroencephalography and Clinical Neurophysiology, 88(1), 12–19.PubMedCrossRef

Vandenbroucke, M. W., Scholte, H. S., van Engeland, H., Lamme, V. A., & Kemner, C. (2008). A neural substrate for atypical low-level visual processing in autism spectrum disorder. Brain, 131(Pt 4), 1013–1024. doi:10.1093/brain/awm321.PubMedCrossRef

Vanni, S., Warnking, J., Dojat, M., Delon-Martin, C., Bullier, J., & Segebarth, C. (2004). Sequence of pattern onset responses in the human visual areas: An fMRI constrained VEP source analysis. Neuroimage, 21(3), 801–817. doi:10.1016/j.neuroimage.2003.10.047.PubMedCrossRef

Vogel, E. K., & Luck, S. J. (2000). The visual N1 component as an index of a discrimination process. Psychophysiology, 37(2), 190–203.PubMedCrossRef

Wechsler, D. (1997). Wechsler Adult Intelligence Scale (Third edition, WAIS-III). San Antonio, TX: The Psychological Corporation.

Wechsler, D. (2005). Wechsler Intelligence Scale for Children (Fourth Edition, WISC-IV). San Antonio, TX: The Psychological Corporation.

Wigham, S., Rodgers, J., South, M., McConachie, H., & Freeston, M. (2015). The interplay between sensory processing abnormalities, intolerance of uncertainty, anxiety and restricted and repetitive behaviours in autism spectrum disorder. Journal of Autism and Developmental Disorders, 45(4), 943–952. doi:10.1007/s10803-014-2248-x.PubMedCrossRef

Wijers, A. A., Lange, J. J., Mulder, G., & Mulder, L. J. (1997). An ERP study of visual spatial attention and letter target detection for isoluminant and nonisoluminant stimuli. Psychophysiology, 34(5), 553–565.PubMedCrossRef

Wong, T. K., Fung, P. C., Chua, S. E., & McAlonan, G. M. (2008). Abnormal spatiotemporal processing of emotional facial expressions in childhood autism: Dipole source analysis of event-related potentials. European Journal of Neuroscience, 28(2), 407–416. doi:10.1111/j.1460-9568.2008.06328.x.PubMedCrossRef

Titel: Brief Report: Early VEPs to Pattern-Reversal in Adolescents and Adults with Autism
Auteurs: K. Kovarski
A. Thillay
E. Houy-Durand
S. Roux
A. Bidet-Caulet
F. Bonnet-Brilhault
M. Batty
Publicatiedatum: 30-07-2016
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 10/2016
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-016-2880-8

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Brief Report: Early VEPs to Pattern-Reversal in Adolescents and Adults with Autism

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